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Eltrombopag Olamine

CAS No. 496775-62-3

Eltrombopag Olamine ( Eltrombopag diethanolamine salt; SB-497115GR )

Catalog No. M18653 CAS No. 496775-62-3

Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 52 In Stock
10MG 83 In Stock
50MG 168 In Stock
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Biological Information

  • Product Name
    Eltrombopag Olamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity.
  • Description
    Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
  • Synonyms
    Eltrombopag diethanolamine salt; SB-497115GR
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Thrombopoietin receptor
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    496775-62-3
  • Formula Weight
    564.63
  • Molecular Formula
    C29H36N6O6
  • Purity
    98%
  • Solubility
    DMSO : ≥ 50 mg/mL; 88.55 mM
  • SMILES
    Cc1c(cc(cc1)n1c(=O)c(c([nH]1)C)N/N=C/1\C=CC=C(C1=O)c1cc(ccc1)C(=O)O)C.C(CO)N.C(CO)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Erickson-Miller CL, et al. Stem Cells, 2009, 27(2), 424-430.
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